GW501506 Cardarine

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Description

GW-501516 also commonly known as Cardarine is a peptide that is classified as a PPAR receptor agonist. Research on the functionality and possible use of this peptide began two decades ago with combined efforts of Ligand pharmaceutical and GlaxoSmithKline.

The main aim of the research was to find a solution to cardiovascular diseases, obesity, and diabetes. According to research Cardarine binds to PPAR receptor, and it recruits a co-activator called PGC-1α enzyme. This enzyme is effective in increasing the expression of genes that are involved in energy expenditure. Mice that were treated with Cardarine showed an increase in fatty acid metabolism and protection against obesity. In other studies done on rhesus negative guinea pigs, Cardarine increased the amount of high-density lipoproteins and decreased low-density lipoproteins. The effect appeared because the peptide caused an increase in the expression of cholesterol transporter ABCA1.

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How it works
Studies have revealed that Cardarine stimulates the skeletal muscle and glucose uptake. Moreover, it stimulates fatty acid oxidation an essential feature in promoting weight loss. Further studies are still underway to determine the effectiveness of the peptide in combating excessive weight gain. It is suggested that Cardarine will be used in treating obesity and promote rapid melting of fat. The peptide is PPARδ agonist, and it binds to these receptors which sense steroidal and thyroid hormones in the body. This initiates PGC-1α enzyme. When the enzyme is activated energy homeostasis in the biological system is regulated.

Cardarine and Weight Loss
The effects of Cardarine are visible on the test subjects. According to studies, the peptide increased the endurance of the test subjects. Increased muscle endurance is an essential part of dealing with fatigue during exercises. In addition, the peptide does not have any catabolic effect which is associated with many thermogenic. When this happens the test subject can burn the fat cells and increase muscle mass without damaging the cells or overworking the body cells. GW-501516 is known to increase nutrient efficiency. This means that muscle and bone development will be enhanced.

Cardarine Dosage
Cardarine will exhibit both fat oxidation and endurance if you manage the dosages effectively. Essentially, it is recommended that you begin with low dose before moving to a higher dosage. The recommended dosage is 20 mg per day for 8 to 12 weeks. However, you can begin with 10 to 15 mg per day as you monitor the response of the test subject. Cardarine is taken orally, and the half-life of the peptide is 20 to 24 hours. This means that a dose once a day will be effective in bringing the desired effects. It is recommended that you squirt the liquid into the mouth of the test subject for increased efficacy.

GW-501516 Availability
Cardarine is available online for sale, and you should take time to find a reputable company to purchase the peptide from, this reduces chances of any damage or lowered efficacy. Cardarine is a research chemical, it is solely used for research purposes, and human consumption is not allowed.

Side Effects of Cardarine
The side effects of Cardarine include increased the risk of cancer; however, there is no conclusive research on this. Studies showed that a high dosage on the rats increased their chances of developing cancer cells. Besides, you can manage this by administering low dosages. Cardarine is not estrogenic. This means that features such as bloating, water retention, gynecomastia, and high blood pressure will not appear at all. Moreover, there will be no conversion of testosterone to estrogen on the test subject. Cardarine has no androgenic effects which showed that hair loss, acne and virilization are not possible in female subjects. Moreover, it is not toxic to the liver.

Based on the positive attributes of the peptide Cardarine is one of the most effective androgen modulators that can accentuate muscle endurance and weight loss. Enhanced recovery is key for performance athletes and studies are still underway to determine the potential of Cardarine in boosting recovery time. The peptide is pretty much everything because it's affinity and binding to receptors is high and effective. Fat loss is one of the features of the peptide, and you will see veins and striations on the test subject after administration of the peptide. A boost in the conversion of nutrients is highly effective because it helps in muscle and bone development.

In conclusion, there are further studies that are being conducted on the efficacy and potency of the peptide. Therefore, human consumption is not yet approved. However, the many benefits and no toxicity on the liver present one of the main advantages of the peptide. Whether you want to carry out research in a laboratory or hospital setting, it is recommended that you select a supplier who is verified and delivers peptides with high purity level. The purity level of the peptide will determine its efficacy and use in benchmarking further studies.