SARMs are a class of androgen receptor ligands which binds to androgen receptors. Scientifically, they are called Selective Androgen Receptor Modulators. Research on this ligand began in the 40’s and this was through the modification of the natural testosterone molecule.
The synthetic peptide was developed to improve disease fighting, improve bone health, decrease obesity and prevent muscles from wasting. RAD 140 also commonly called Testolone is a modern SARM and the first studies were published in 2010. Following the discovery of the peptide, researchers have been conducting further tests to determine the efficiency of the peptide in producing known effects.
The main reason why the peptide is produced is that it has shown to be effective in accentuating the production of growth hormones from the anterior lobe of the pituitary gland. Research done on mice has shown that RAD 140 is effective in two aspects: one is that depending on the dose, there was significant tissue and muscle growth. The second aspect is that there were no adverse side effects on the test subjects.
Mechanism of Action
RAD 140 is a non-steroidal selective androgen receptor modular and because of the selective nature which works on the muscles. This means that the other body tissues will not experience any negative side effects. The peptide works by accentuating the production of male hormone testosterone and this will generate anabolic effects without estrogenic side effects. Research done on mice indicated that RAD 140 had greater anabolic effects than testosterone. The peptide increases muscle mass and it bridges the gap between steroid cycle. The peptide increases anabolic effects of any peptide that you administer to the test subject. RAD 140 is more effective than any other prohormones in the market in reinforcing the effects of testosterone without damaging the liver.
The peptide can be administered in tablet, capsule or tincture module. Depending on the mode of administration, you will see the effects it has on the test subjects. The peptide accentuates natural production of testosterone and this mimics the natural testosterone effects. One of the main features of RAD 140 is that it is highly selective in nature and it has mild to zero effect as experienced in anabolic androgenic steroids. RAD 140 interacts with androgenic receptors in bones and tissues, therefore it does not activate receptors in other parts of the body. Continuing research is geared towards reaping much from the peptide because of its selective nature. It will be safe for use in female test subjects without causing too much androgenicity.
How it works
Apart from the non-steroidal nature of the hormone with few side effects, there are several reasons that the product could be great in combating various conditions. RAD 140 is known to improve stamina according to muscle cells of mice studied under probes. There is a potential breakthrough in the use of the peptide to accentuate muscle development because the peptide showed a higher potency and efficacy in stimulating myoblasts differentiation.
RAD 140 Dosages
The dosage of RAD 140 varies from one test subject to another because of the level of tolerance and sensitivity to the peptide. The objective of using any peptide during research is to achieve an optimal dosage that will work perfectly without compromising the safety parameters. Recent research studies indicate that dosages from 0.3 mg to 30 mg a day can be administered to the test subject. It is important that when conducting research, you begin with low dosages as you move to higher ones because this will help the body of the test subject build tolerance. Otherwise, the test subject will experience adverse side effects.
According to studies done on mice, RAD 140 has neuroprotective properties and in the research mice that were administered with the peptide showed a higher preservation of neural cells than placebo. The peptide preserves neurons and this could be further investigated to ascertain its use in healing or combating degenerative diseases. In some cases where neurological problems are caused by androgenic deficiencies, the peptide could be effective in reversing the effect.
Programmed cell death is called apoptosis. In early stages or research, RAD 140 has been shown to reduce cell death. When the cells are regulated, there will be no unprecedented cell death which could be severe. Moreover, natural testosterone protects the neurons and this will transfer information to the brain to promote cell division.
According to studies done on mice, it indicated that administration of RAD 140 showed an increased muscle mass. The mice were administered with the peptide, and their muscle growth were monitored using X-ray and other machinery to measure muscle cell division and development. The peptide reduced fat content on the muscles and this promotes increased muscle mass. RAD 140 comes in easy to use liquid form and you can administer it to the mouth of the test subject and monitor the effects on the test subject.
Possible Side Effects
It is important to note that RAD 140 has possible side effects and researchers are looking at different dosages and their side effects. The common side effects include nausea, vomiting, bloating, swelling, redness and itching.
In summary, RAD 140 is the most promising SARM of all time and it has set a base for research for better peptides to be produced. There is a potential that this could be the most powerful and potent supplement in enhancing muscle building, reducing neurodegenerative diseases and boosting strength. With a higher level of bioavailability, you will be able to achieve the desired results by administering RAD 140 to the test subjects.